Individualized recovery of gut microbial strains post antibiotics
نویسندگان
چکیده
منابع مشابه
Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation.
The indigenous human microbiota is essential to the health of the host. Although the microbiota can be affected by many features of modern life, we know little about its responses to disturbance, especially repeated disturbances, and how these changes compare with baseline temporal variation. We examined the distal gut microbiota of three individuals over 10 mo that spanned two courses of the a...
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In spite of their unusual molecular structures and seemingly high degree of biological recalcitrance, many antibiotics have been shown to be susceptible to microbial attack. Among the types of changes brought about by microbial systems are: (i) acylation; (ii) phosphorylation; (iii) adenylylation and ribonucleotide formation; (iv) hydrolysis; (v) oxidation; (vi) suiph oxidation; (vii) reduction...
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Intestinal bacteria carry out many fundamental roles, such as the fermentation of non-digestible dietary carbohydrates to produce short chain fatty acids (SCFAs), which can affect host energy levels and gut hormone regulation. Understanding how to manage this ecosystem to improve human health is an important but challenging goal. Antibiotics are the front line of defence against pathogens, but ...
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The effects of antibiotics on the indigenous microbes of the gut have been the subject of extensive study ever since the discovery of these drugs in the 1940s and their subsequent commercial production. Yet nearly all of this work has concerned the effects of individual antibiotics on individual, cultivated strains of bacteria in the laboratory, or on specific species of bacteria cultivated fro...
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ژورنال
عنوان ژورنال: npj Biofilms and Microbiomes
سال: 2019
ISSN: 2055-5008
DOI: 10.1038/s41522-019-0103-8